Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687095 | 0.80 | ILK (0.54) | ILKGSK3B | |
| SCHEMBL687104 | 0.78 | ILK (0.64) | ILKGSK3B | |
| SCHEMBL686526 | 0.75 | ILK (0.60) | ILKGSK3B | |
| SCHEMBL686491 | 0.73 | ILK (0.64) | ILK | |
| SCHEMBL686426 | 0.73 | ILK (0.69) | ILK | |
| SCHEMBL687229 | 0.73 | ILK (0.64) | ILK | |
| SCHEMBL686915 | 0.72 | ILK (0.72) | ILK | |
| SCHEMBL686598 | 0.72 | ILK (1.00) | ILK | |
| SCHEMBL2163407 | 0.72 | ILK (0.73) | ILK | |
| SCHEMBL687278 | 0.71 | ILK (1.00) | ILKGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542997-B1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | DERMIRA CANADA INC (CA) | 2012-02-29 | — | — | EP | disclosed |