Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.58 |
| ▸ | HTR2B | P41595 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875276 | 1.00 | MCHR1 (0.58) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| Hydrochloric Acid SCHEMBL6460220 | 0.85 | MCHR1 (0.76) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| Hydrochloric Acid SCHEMBL6460225 | 0.85 | MCHR1 (0.76) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL6873248 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL6873245 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| Trifluoroacetic Acid SCHEMBL6462100 | 0.84 | MCHR1 (0.58) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| Hydrochloric Acid SCHEMBL6466912 | 0.84 | MCHR1 (0.76) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL6463257 | 0.84 | MCHR1 (0.78) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL6463252 | 0.84 | MCHR1 (0.78) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| Hydrochloric Acid SCHEMBL6466908 | 0.84 | MCHR1 (0.76) | MCHR1ADRA2AHRH1ADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |