Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875295 | 1.00 | MCHR1 (0.40) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6879711 | 0.91 | MEN1 (0.53) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6879704 | 0.91 | MEN1 (0.53) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6868513 | 0.90 | NPSR1 (0.50) | MCHR1ADRA2AHRH1HTR2BCYP1A2 | |
| SCHEMBL6868508 | 0.90 | NPSR1 (0.50) | MCHR1ADRA2AHRH1HTR2BCYP1A2 | |
| SCHEMBL6456505 | 0.89 | MCHR1 (0.39) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6456511 | 0.89 | MCHR1 (0.39) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6875336 | 0.89 | GAA (0.42) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6875342 | 0.89 | GAA (0.42) | MCHR1ADRA2AHRH1HTR2BMEN1 | |
| SCHEMBL6879619 | 0.88 | MCHR1 (0.40) | MCHR1ADRA2AHRH1HTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |