Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875315 | 1.00 | CCNT1 (0.43) | CCNT1CCNT2CCNE2CCNE1CDK2 | |
| SCHEMBL6877408 | 0.89 | MAPK8 (0.42) | CDK2MCHR1ADRA2ANPY5RMAPK8 | |
| SCHEMBL6457586 | 0.89 | MAPK8 (0.42) | CDK2MCHR1ADRA2ANPY5RMAPK8 | |
| SCHEMBL6460395 | 0.86 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1MAPT | |
| SCHEMBL6460406 | 0.86 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1MAPT | |
| SCHEMBL6873584 | 0.86 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RALDH1A1HTT | |
| SCHEMBL6873577 | 0.86 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RALDH1A1HTT | |
| SCHEMBL6875477 | 0.85 | KCNH2 (0.43) | CDK2MCHR1ADRA2ANPY5RMAPK8 | |
| SCHEMBL6455824 | 0.85 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6876612 | 0.85 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |