Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 14/20 | 0.48 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688406 | 1.00 | PTGER3 (0.48) | PTGER3CTSALCKALDH1A1KDM4E | |
| SCHEMBL687117 | 0.93 | PTGER3 (0.52) | PTGER3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL687524 | 0.93 | PTGER3 (0.45) | PTGER3CTSALCKALDH1A1KDM4E | |
| SCHEMBL687411 | 0.92 | PTGER3 (0.42) | PTGER3ALDH1A1KDM4E | |
| SCHEMBL688236 | 0.90 | PTGER3 (0.47) | PTGER3LCKALDH1A1KDM4EMAPT | |
| SCHEMBL687904 | 0.89 | PTGER3 (0.47) | PTGER3CTSAALDH1A1KMT2AMAPT | |
| SCHEMBL686938 | 0.88 | PTGER3 (0.47) | PTGER3CTSALCKALDH1A1GCGR | |
| SCHEMBL687114 | 0.88 | PTGER3 (0.45) | PTGER3CTSAALDH1A1MAPT | |
| SCHEMBL688250 | 0.88 | PTGER3 (0.45) | PTGER3CTSAALDH1A1MAPTRXFP1 | |
| SCHEMBL687672 | 0.87 | CYP26A1 (0.43) | PTGER3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |