Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 8/20 | 0.47 |
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686799 | 0.93 | PTGER3 (0.51) | PTGER3CTSATHRBCNR2SLC22A12 | |
| SCHEMBL686846 | 0.93 | PTGER3 (0.41) | PTGER3CTSAALDH1A1CYP26A1CNR2 | |
| SCHEMBL686842 | 0.93 | PTGER3 (0.45) | PTGER3CTSALCKALDH1A1THRB | |
| SCHEMBL687791 | 0.91 | PTGER3 (0.43) | PTGER3CTSAALDH1A1THRBHPGD | |
| SCHEMBL687310 | 0.90 | CTSA (0.39) | PTGER3CTSAGCGRALDH1A1THRB | |
| SCHEMBL688343 | 0.89 | PTGER3 (0.43) | PTGER3CTSAP2RX7RXFP1CNR2 | |
| SCHEMBL688233 | 0.89 | PTGER3 (0.43) | PTGER3CTSAP2RX7RXFP1CYP26A1 | |
| SCHEMBL688170 | 0.88 | PTGER3 (0.41) | PTGER3ALDH1A1RXFP1CYP26A1CNR2 | |
| SCHEMBL687540 | 0.88 | PTGER3 (0.48) | PTGER3CTSAGCGRLCKALDH1A1 | |
| SCHEMBL688406 | 0.88 | PTGER3 (0.48) | PTGER3CTSAGCGRLCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |