Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875428 | 1.00 | MCHR1 (0.43) | MCHR1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL6464423 | 0.94 | MCHR1 (0.40) | MCHR1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL6877053 | 0.94 | KDR (0.42) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A | |
| SCHEMBL6464416 | 0.94 | MCHR1 (0.40) | MCHR1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL6877062 | 0.94 | KDR (0.42) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A | |
| SCHEMBL6464055 | 0.94 | MCHR1 (0.42) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A | |
| SCHEMBL6464046 | 0.94 | MCHR1 (0.42) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A | |
| SCHEMBL6467746 | 0.93 | MCHR1 (0.40) | MCHR1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL6467739 | 0.93 | MCHR1 (0.40) | MCHR1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL6463927 | 0.93 | MCHR1 (0.39) | MCHR1KDM4ELMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |