Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 15/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875445 | 1.00 | KMT2A (0.47) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6458231 | 0.94 | KMT2A (0.54) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6458222 | 0.94 | KMT2A (0.54) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6880206 | 0.90 | MCHR1 (0.40) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6880209 | 0.90 | MCHR1 (0.40) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6873382 | 0.89 | KMT2A (0.44) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6877651 | 0.87 | EPHX2 (0.44) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6877658 | 0.87 | EPHX2 (0.44) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6869037 | 0.85 | KMT2A (0.52) | KMT2AMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6875520 | 0.85 | MCHR1 (0.44) | KMT2AMCHR1ADRA2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |