Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.64 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875663 | 1.00 | CNR1 (0.64) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6866987 | 0.91 | CNR1 (0.77) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6866978 | 0.91 | CNR1 (0.77) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6875388 | 0.90 | MCHR1 (0.64) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6875382 | 0.90 | MCHR1 (0.64) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6874799 | 0.89 | MCHR1 (0.79) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6874796 | 0.89 | MCHR1 (0.79) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6464648 | 0.89 | MCHR1 (0.62) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6464646 | 0.89 | MCHR1 (0.62) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL7037171 | 0.88 | MCHR1 (0.63) | CNR1KCNH2AURKBMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |