Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463136 | 0.90 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463133 | 0.90 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6457744 | 0.90 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL6457739 | 0.90 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL6878417 | 0.89 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6878421 | 0.89 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6872722 | 0.85 | HDAC3 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6872721 | 0.85 | HDAC3 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463174 | 0.85 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RSMN1; SMN2ADRA1A | |
| SCHEMBL13793236 | 0.85 | MCHR1 (0.65) | MCHR1ADRA2ANPY5RADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |