Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 1.00 |
| ▸ | CTSS | P25774 | 11/20 | 1.00 |
| ▸ | CTSB | P07858 | 7/20 | 1.00 |
| ▸ | CTSK | P43235 | 5/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.62 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.57 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525339 | 1.00 | CTSL (1.00) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5530445 | 1.00 | CTSL (1.00) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL6867271 | 1.00 | CTSL (1.00) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5518266 | 0.92 | CTSL (0.85) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5520437 | 0.92 | CTSL (0.85) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5522179 | 0.91 | CTSL (0.83) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5521614 | 0.91 | CTSL (0.83) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5520689 | 0.90 | CTSL (0.82) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5534375 | 0.90 | CTSL (0.82) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL5522964 | 0.90 | CTSL (0.81) | CTSLCTSSCTSBCTSKCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |