Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875819 | 1.00 | PPID (0.41) | PPIDMCHR1ACACBACACAMDM2 | |
| SCHEMBL6875811 | 1.00 | PPID (0.41) | PPIDMCHR1ACACBACACAMDM2 | |
| SCHEMBL6876320 | 0.90 | MCHR1 (0.41) | PPIDMCHR1ADRA2A | |
| SCHEMBL5530254 | 0.85 | MCHR1 (0.52) | MCHR1NPY5RADRA2A | |
| SCHEMBL5530257 | 0.85 | MCHR1 (0.52) | MCHR1NPY5RADRA2A | |
| SCHEMBL5530248 | 0.85 | MCHR1 (0.52) | MCHR1NPY5RADRA2A | |
| SCHEMBL6460344 | 0.83 | PTGIR (0.48) | MCHR1ACACBACACANPY5RADRA2A | |
| SCHEMBL6460333 | 0.83 | PTGIR (0.48) | MCHR1ACACBACACANPY5RADRA2A | |
| SCHEMBL6878604 | 0.82 | MCHR1 (0.48) | MCHR1ACACBACACANPY5RADRA2A | |
| SCHEMBL6878610 | 0.82 | MCHR1 (0.48) | MCHR1ACACBACACANPY5RADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |