Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632422 | 0.91 | ALDH1A1 (0.43) | MCHR1ADRA2ARAB9A | |
| SCHEMBL6875811 | 0.90 | PPID (0.41) | MCHR1PPIDADRA2A | |
| SCHEMBL6875819 | 0.90 | PPID (0.41) | MCHR1PPIDADRA2A | |
| SCHEMBL6875816 | 0.90 | PPID (0.41) | MCHR1PPIDADRA2A | |
| SCHEMBL6867518 | 0.90 | ELANE (0.44) | MCHR1ADRA2A | |
| SCHEMBL6867524 | 0.90 | ELANE (0.44) | MCHR1ADRA2A | |
| SCHEMBL5527236 | 0.84 | MCHR1 (0.55) | MCHR1ADRA2A | |
| SCHEMBL5527235 | 0.84 | MCHR1 (0.55) | MCHR1ADRA2A | |
| SCHEMBL5527239 | 0.84 | MCHR1 (0.55) | MCHR1ADRA2A | |
| SCHEMBL6456527 | 0.83 | TACR3 (0.47) | MCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |