Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875847 | 1.00 | KMT2A (0.60) | KMT2ALMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL6873913 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2GAAMEN1MAPT | |
| SCHEMBL6873906 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2GAAMEN1MAPT | |
| SCHEMBL6465993 | 0.89 | KMT2A (0.46) | KMT2ALMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL6465997 | 0.89 | KMT2A (0.46) | KMT2ALMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL6874169 | 0.87 | MCHR1 (0.45) | KMT2ALMNASMN1; SMN2GAAMAPT | |
| SCHEMBL6874165 | 0.87 | MCHR1 (0.45) | KMT2ALMNASMN1; SMN2GAAMAPT | |
| SCHEMBL6876089 | 0.85 | TSHR (0.57) | KMT2ASMN1; SMN2MAPTMCHR1POLB | |
| SCHEMBL6876093 | 0.85 | TSHR (0.57) | KMT2ASMN1; SMN2MAPTMCHR1POLB | |
| SCHEMBL6872847 | 0.83 | EPHX2 (0.47) | KMT2ASMN1; SMN2MEN1MCHR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |