Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875915 | 1.00 | MCHR1 (0.49) | MCHR1TP53ADRA2ARAB9AHTR1A | |
| SCHEMBL6875248 | 0.92 | MCHR1 (0.49) | MCHR1TP53ADRA2ARAB9AHTR1A | |
| SCHEMBL6875245 | 0.92 | MCHR1 (0.49) | MCHR1TP53ADRA2ARAB9AHTR1A | |
| SCHEMBL6876569 | 0.86 | RAB9A (0.48) | MCHR1TP53ADRA2ARAB9AHTR1A | |
| SCHEMBL6876563 | 0.86 | RAB9A (0.48) | MCHR1TP53ADRA2ARAB9AHTR1A | |
| SCHEMBL6877538 | 0.85 | MCHR1 (0.53) | MCHR1ADRA2ARAB9AHTR1AADRA1A | |
| SCHEMBL6877534 | 0.85 | MCHR1 (0.53) | MCHR1ADRA2ARAB9AHTR1AADRA1A | |
| SCHEMBL6875053 | 0.84 | MCHR1 (0.49) | MCHR1ADRA2ARAB9A | |
| SCHEMBL6875056 | 0.84 | MCHR1 (0.49) | MCHR1ADRA2ARAB9A | |
| SCHEMBL27651773 | 0.84 | MCHR1 (0.52) | MCHR1ADRA2ARAB9AHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |