SCHEMBL687612

SCHEMBL687612

CC(C=O)=CN(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419480 1.00
SCHEMBL12547389 1.00
SCHEMBL19159445 0.86 TSHR (0.33)
SCHEMBL8529188 0.73 TSHR (0.32)
SCHEMBL8529187 0.73 TSHR (0.32)
SCHEMBL24717060 0.71
SCHEMBL359274 0.71
SCHEMBL14517001 0.71 TSHR (0.30)
SCHEMBL13548320 0.69 TSHR (0.33)
SCHEMBL10238630 0.69 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379645-B1 ISOLATION OF DNA MOLECULES USING MERCAPTO-ARYL LIGANDS GE HEALTHCARE BIO SCIENCES AB (SE) 2010-06-23 EP claimed
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
JP-58038298-A None JP disclosed
US-12358931-B2 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl) propanenitrile as a JAK kinase inhibitor THERAVANCE BIOPHARMA R&D IP, LLC (US) 2025-07-15 US disclosed
CN-116813449-B Phosphorus coordinated iridium monoatomic catalyst for preparing unsaturated alcohol by selective hydrogenation of alpha, beta-unsaturated aldehyde 中国科学院化学研究所 2024-07-12 CN disclosed
EP-3762392-B1 THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME WELLMARKER BIO CO LTD (KR) 2024-05-15 EP disclosed
US-20240132520-A1 NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2024-04-25 US disclosed
US-11780852-B2 Methods for treating Crohn's disease using 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-10-10 US disclosed
CN-116813449-A Phosphorus coordinated iridium monoatomic catalyst for preparing unsaturated alcohol by selective hydrogenation of alpha, beta-unsaturated aldehyde 中国科学院化学研究所 2023-09-29 CN disclosed
WO-2023151642-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 WO disclosed
WO-1996033170-A1 N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS NOVARITS AG (CH) 1996-10-24 WO disclosed
WO-1996030377-A1 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1996-10-03 WO disclosed
WO-1996015112-A1 AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION ACEA PHARMACEUTICALS, INC. (US) 1996-05-23 WO disclosed
US-5476933-A Condensation, ring expansion STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) 1995-12-19 US disclosed
EP-0161418-B1 ANTIMICROBIAL AGENTS CONTAINING 2-(1H-PYRAZOL-1-YL)-4-(3H)-QUINAZOLINONES BAYER AG (DE) 1988-09-07 EP disclosed
US-4644000-A FUNGICIDES, BACTERICIDES, SLIMICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-02-17 US disclosed
EP-0161418-A1 Antimicrobial agents containing 2-(1H-pyrazol-1-yl)-4-(3H)-quinazolinones BAYER AG (DE) 1985-11-21 EP disclosed
JP-S5838298-A PREPARATION OF COBALT COMPOUND OF TETRAAZAANNULENE ASAHI CHEM IND CO LTD 1983-03-05 JP disclosed
US-4239760-A Combating fungi and bacteria with 3-azolyl-benzo-1,2,4-triazines and 1-oxides thereof BAYER AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed