SCHEMBL8529187

SCHEMBL8529187

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529188 1.00 TSHR (0.32) TSHRTRPA1
SCHEMBL19304235 0.73 TSHR (0.30) TSHR
SCHEMBL12547389 0.73
SCHEMBL687612 0.73
SCHEMBL419480 0.73
SCHEMBL12809498 0.73
SCHEMBL10048777 0.73
SCHEMBL18820398 0.71 ALDH1A1 (0.39) TSHRTRPA1
SCHEMBL13934126 0.70
SCHEMBL10643984 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873746-A2 Dyestuff for keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed
EP-0873746-A2 Dyestuff for keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP disclosed