Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876280 | 1.00 | MEN1 (0.42) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6877441 | 0.91 | GAA (0.47) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6867662 | 0.91 | MEN1 (0.54) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6877436 | 0.91 | GAA (0.47) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6867670 | 0.91 | MEN1 (0.54) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6872137 | 0.90 | MCHR1 (0.41) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6872140 | 0.90 | MCHR1 (0.41) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6876785 | 0.89 | KMT2A (0.58) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6876780 | 0.89 | KMT2A (0.58) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6880792 | 0.89 | MCHR1 (0.42) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |