Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877436 | 1.00 | GAA (0.47) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL6876284 | 0.91 | MEN1 (0.42) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL6876280 | 0.91 | MEN1 (0.42) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL6872487 | 0.90 | ALOX12 (0.56) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6867662 | 0.89 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1MCHR1 | |
| SCHEMBL6459476 | 0.89 | GAA (0.47) | GAAL3MBTL1MAPTMCHR1ADRA2A | |
| SCHEMBL6459471 | 0.89 | GAA (0.47) | GAAL3MBTL1MAPTMCHR1ADRA2A | |
| SCHEMBL6867670 | 0.89 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1MCHR1 | |
| SCHEMBL6872137 | 0.89 | MCHR1 (0.41) | MEN1KMT2ALMNAMCHR1ADRA2A | |
| SCHEMBL6872140 | 0.89 | MCHR1 (0.41) | MEN1KMT2ALMNAMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |