Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | GPR6 | P46095 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | WHR1 | P49842 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6929267 | 0.93 | KDM4E (0.61) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6456694 | 0.80 | KDM4E (0.67) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6456699 | 0.80 | KDM4E (0.67) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6876795 | 0.79 | KDM4E (0.50) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6461755 | 0.79 | KDM4E (0.70) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6461750 | 0.79 | KDM4E (0.70) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6455648 | 0.79 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6461404 | 0.79 | KDM4E (0.65) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6461402 | 0.79 | KDM4E (0.65) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6460864 | 0.78 | LMNA (0.54) | KDM4ESMN1; SMN2LMNAMCHR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |