Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052295 | 0.92 | TSHR (0.45) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL19225929 | 0.85 | EGLN1 (0.47) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL20418703 | 0.74 | TSHR (0.59) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL15251729 | 0.74 | TSHR (0.59) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL629930 | 0.74 | TSHR (0.59) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL10062407 | 0.73 | TSHR (0.58) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL6259204 | 0.73 | TSHR (0.58) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL4877662 | 0.73 | TSHR (0.58) | GLATSHRFABP7FABP5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7406170 | 0.73 | TSHR (0.62) | GLATSHRFABP7FABP5ALDH1A1 | |
| SCHEMBL27821456 | 0.72 | TSHR (0.48) | TSHRFABP7FABP5ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029237-A1 | Process for preparing n-substituted 4-hydroxypiperidines by enzymatic hudroxylation | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2004-02-12 | — | — | US | disclosed |
| EP-1319085-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 4-HYDROXYPIPERIDINES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002022845-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 4-HYDROXYPIPERIDINES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2002-03-21 | — | — | WO | disclosed |
| EP-1188837-A1 | Process for preparing N-substituted 4-hydroxypiperidines by enzymatic hydroxylation | Eidgenössische Technische Hochschule Zürich (CH) | 2002-03-20 | — | — | EP | disclosed |