Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 15/20 | 1.00 |
| ▸ | PDE4A | P27815 | 14/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 14/20 | 1.00 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876779 | 1.00 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL6876774 | 1.00 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL6453683 | 0.91 | PDE4B (0.84) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL5557664 | 0.91 | PDE4B (0.84) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL6453687 | 0.91 | PDE4B (0.84) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL5557668 | 0.91 | PDE4B (0.84) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| Hydrochloric Acid SCHEMBL4015397 | 0.90 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| Hydrochloric Acid SCHEMBL4015390 | 0.90 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| Hydrochloric Acid SCHEMBL4015395 | 0.90 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL6244831 | 0.88 | PDE4D (0.79) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042319-B1 | DIHYDROBENZOFURANS | ALTANA PHARMA AG (DE) | 2004-02-04 | — | — | EP | disclosed |
| US-6380196-B1 | BRONCHIAL THERAPEUTICS, BRONCHIAL DILATORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-04-30 | — | — | US | disclosed |