Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 13/20 | 0.70 |
| ▸ | APP | P05067 | 6/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686453 | 0.89 | ILK (0.70) | ILK | |
| SCHEMBL687116 | 0.84 | ILK (0.70) | ILKAPP | |
| SCHEMBL686420 | 0.84 | ILK (0.70) | ILKAPP | |
| SCHEMBL686711 | 0.83 | ILK (1.00) | ILK | |
| SCHEMBL686870 | 0.81 | ILK (0.70) | ILK | |
| SCHEMBL687517 | 0.81 | ILK (0.72) | ILKAPP | |
| SCHEMBL2165867 | 0.81 | ILK (0.72) | ILKGFER | |
| SCHEMBL686899 | 0.81 | ILK (0.57) | ILKAPP | |
| SCHEMBL686473 | 0.80 | ILK (0.76) | ILK | |
| SCHEMBL686813 | 0.80 | ILK (0.73) | ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542997-B1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | DERMIRA CANADA INC (CA) | 2012-02-29 | — | — | EP | disclosed |