Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877001 | 1.00 | HDAC2 (0.47) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6877004 | 1.00 | HDAC2 (0.47) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6852464 | 0.80 | HDAC2 (0.49) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6852468 | 0.80 | HDAC2 (0.49) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6850604 | 0.73 | HDAC2 (0.56) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6850598 | 0.73 | HDAC2 (0.56) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6869462 | 0.73 | DPP4 (0.53) | LTA4HHDAC1DPP4PPARG | |
| SCHEMBL6869460 | 0.73 | DPP4 (0.53) | LTA4HHDAC1DPP4PPARG | |
| SCHEMBL13790222 | 0.73 | HDAC2 (0.64) | HDAC2LTA4HCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6851704 | 0.73 | NEK2 (0.44) | HDAC2CYP17A1CYP11B1CYP11B2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |