Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457784 | 0.90 | EPHX2 (0.50) | MCHR1ADRA2ANPY5REPHX2 | |
| SCHEMBL6457777 | 0.90 | EPHX2 (0.50) | MCHR1ADRA2ANPY5REPHX2 | |
| SCHEMBL6873156 | 0.90 | LMNA (0.55) | MCHR1ADRA2ALMNANPSR1ALOX12 | |
| SCHEMBL6873160 | 0.90 | LMNA (0.55) | MCHR1ADRA2ALMNANPSR1ALOX12 | |
| SCHEMBL6460463 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6460454 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6877819 | 0.88 | LMNA (0.42) | MCHR1ADRA2ALMNANPSR1ALOX12 | |
| SCHEMBL6877814 | 0.88 | LMNA (0.42) | MCHR1ADRA2ALMNANPSR1ALOX12 | |
| SCHEMBL6463384 | 0.87 | LMNA (0.57) | LMNANPSR1ALOX12ALDH1A1THRB | |
| SCHEMBL6463386 | 0.87 | LMNA (0.57) | LMNANPSR1ALOX12ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |