Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877337 | 1.00 | HDAC4 (0.37) | HDAC4DHODHEP300PRMT5WDR77 | |
| SCHEMBL6877341 | 1.00 | HDAC4 (0.37) | HDAC4DHODHEP300PRMT5WDR77 | |
| SCHEMBL6848074 | 0.81 | HDAC4 (0.39) | HDAC4DHODHPRMT5WDR77WNT3A | |
| SCHEMBL6848069 | 0.81 | HDAC4 (0.39) | HDAC4DHODHPRMT5WDR77WNT3A | |
| SCHEMBL6848093 | 0.80 | CYP1A2 (0.42) | DHODH | |
| SCHEMBL6848094 | 0.80 | CYP1A2 (0.42) | DHODH | |
| SCHEMBL6848097 | 0.80 | CYP1A2 (0.42) | DHODH | |
| SCHEMBL6851894 | 0.76 | HDAC4 (0.43) | HDAC4DHODHEP300PRMT5WDR77 | |
| SCHEMBL6851881 | 0.76 | HDAC4 (0.43) | HDAC4DHODHEP300PRMT5WDR77 | |
| SCHEMBL6879073 | 0.74 | ADRB2 (0.42) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |