Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877434 | 1.00 | CARM1 (0.49) | CARM1PRMT6MCHR1ADRA2ARIPK2 | |
| SCHEMBL6875280 | 0.86 | MCHR1 (0.50) | CARM1PRMT6MCHR1ADRA2ARIPK2 | |
| SCHEMBL6875273 | 0.86 | MCHR1 (0.50) | CARM1PRMT6MCHR1ADRA2ARIPK2 | |
| SCHEMBL13795469 | 0.85 | MCHR1 (0.67) | CARM1PRMT6MCHR1ADRA2ANPY5R | |
| SCHEMBL6877508 | 0.84 | MCHR1 (0.59) | CARM1PRMT6MCHR1ADRA2ARIPK2 | |
| SCHEMBL6877502 | 0.84 | MCHR1 (0.59) | CARM1PRMT6MCHR1ADRA2ARIPK2 | |
| SCHEMBL6456562 | 0.82 | MCHR1 (0.47) | CARM1PRMT6MCHR1ADRA2ANPY5R | |
| Trifluoroacetic Acid SCHEMBL6455401 | 0.80 | MCHR1 (0.49) | CARM1PRMT6MCHR1ADRA2ANPY5R | |
| SCHEMBL6459651 | 0.80 | MCHR1 (0.67) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6459661 | 0.80 | MCHR1 (0.67) | MCHR1ADRA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |