SCHEMBL6877634

SCHEMBL6877634

O=CNCCC(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
CYP2D6 P10635 1/20 0.44
SRC P12931 2/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR1 P21554 3/20 0.40
CNR2 P34972 3/20 0.40
EPHX2 P34913 1/20 0.40
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH7 P40394 1/20 0.40
TBXAS1 P24557 2/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 1/20 0.39
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3667900 0.82 CYP2C19 (0.53) CYP2C19CYP2D6SRCSMN1; SMN2ADH1B
SCHEMBL11546369 0.80 CYP2C19 (0.55) CYP2C19CYP2D6SRCSMN1; SMN2TBXAS1
SCHEMBL8196240 0.80 HTR2A (0.55) CYP2C19CYP2D6MTNR1AMTNR1BSMN1; SMN2
SCHEMBL30371912 0.79 CYP2C19 (0.61) CYP2C19CYP2D6SRCSMN1; SMN2TBXAS1
SCHEMBL23625038 0.79 KDM4E (0.52) CYP2C19MTNR1AMTNR1BSMN1; SMN2ADH1B
SCHEMBL4450825 0.79 HTR2A (0.60) CYP2C19CYP2D6MTNR1AMTNR1BSMN1; SMN2
SCHEMBL14342900 0.78 CYP2C19 (0.45) CYP2C19CYP2D6MTNR1AMTNR1BSMN1; SMN2
SCHEMBL9333135 0.77 KDM4E (0.59) SMN1; SMN2ALDH1A1
SCHEMBL9333117 0.77 KDM4E (0.59) SMN1; SMN2ALDH1A1
SCHEMBL2112017 0.77 CYP2C19 (0.44) CYP2C19CYP2D6MTNR1AMTNR1BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427703-A1 PYRIDINIUM-BETAIN COMPOUNDS AS TASTE ENHANCER SOCIETE DES PRODUITS NESTLE S.A. (CH) 2004-06-16 EP disclosed
WO-2003022817-A1 PYRIDINIUM-BETAIN COMPOUNDS AS TASTE ENHANCER SOCIETE DES PRODUITS NESTLE S.A. (CH) 2003-03-20 WO disclosed