Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371912 | 0.82 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2CYP2D6LMNAPOLB | |
| SCHEMBL11480585 | 0.81 | TAAR1 (0.52) | HTR2AHRH1SLC6A4CYP2C19SMN1; SMN2 | |
| SCHEMBL17690256 | 0.80 | HTR2A (0.44) | HTR2AHRH1SLC6A4SMN1; SMN2SLC6A2 | |
| SCHEMBL13544535 | 0.79 | SLC6A3 (0.50) | CYP2C19MTNR1AMTNR1BSMN1; SMN2SLC6A3 | |
| SCHEMBL6877634 | 0.79 | CYP2C19 (0.50) | CYP2C19MTNR1AMTNR1BSMN1; SMN2CYP2D6 | |
| SCHEMBL19228532 | 0.79 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL643461 | 0.79 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29182065 | 0.78 | CNR1 (0.60) | CYP2C19MTNR1AMTNR1BSMN1; SMN2CYP1A2 | |
| SCHEMBL8761469 | 0.78 | EPHX2 (0.52) | HTR2AHRH1SMN1; SMN2SLC6A2KMT2A | |
| SCHEMBL29182093 | 0.77 | EPHX2 (0.73) | CYP2C19SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154804-A2 | TWIN FLUOROPHORE PEPTIDE NUCLEIC ACID HYBRIDIZATION PROBES | THOMAS JEFFERSON UNIVERSITY (US) | 2009-12-23 | — | — | WO | disclosed |
| US-6921822-B2 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-07-26 | — | — | US | disclosed |
| US-20040030181-A1 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030181-A1 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | HPD, GRHPR, CYP4B1 | HTR2A 2070/4885HRH1 1988/4885SLC6A4 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.