Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877213 | 0.93 | GHSR (0.65) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL6875340 | 0.82 | GHSR (0.82) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL6879137 | 0.82 | GHSR (0.65) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL805025 | 0.81 | GHSR (0.72) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL2731336 | 0.81 | GHSR (0.81) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL6877112 | 0.81 | GHSR (0.75) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL13552233 | 0.80 | GHSR (0.75) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL6875688 | 0.79 | GHSR (0.72) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL6874832 | 0.79 | GHSR (0.63) | GHSRCYP3A4CYP2D6 | |
| SCHEMBL13552243 | 0.79 | GHSR (0.72) | GHSRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050276-A1 | METHODS OF USING MACROCYCLIC INHIBITORS OF SERINE PROTEASE ENZYMES | TRANZYME PHARMA, INC. (US) | 2011-04-28 | — | — | WO | disclosed |