Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 9/20 | 0.41 |
| ▸ | CTSA | P10619 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686806 | 0.89 | PTGER3 (0.45) | CNR2PTGER3CTSA | |
| SCHEMBL29371834 | 0.88 | PTGER3 (0.44) | CNR2PTGER3CTSA | |
| SCHEMBL686896 | 0.88 | PTGER3 (0.44) | CNR2PTGER3CTSA | |
| SCHEMBL686663 | 0.88 | PTGER3 (0.44) | CNR2PTGER3CTSA | |
| SCHEMBL687998 | 0.87 | CNR2 (0.43) | CNR2PTGER3CTSAKDM4EALDH1A1 | |
| SCHEMBL688458 | 0.87 | PTGER3 (0.43) | CNR2PTGER3CTSA | |
| SCHEMBL687023 | 0.87 | SMN1; SMN2 (0.41) | CNR2PTGER3NPSR1 | |
| SCHEMBL688665 | 0.86 | PTGER3 (0.39) | CNR2PTGER3CTSANPSR1 | |
| SCHEMBL687127 | 0.85 | PTGER3 (0.42) | CNR2PTGER3CTSA | |
| SCHEMBL686657 | 0.85 | CTSA (0.37) | CTSAKDM4EALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |