Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 7/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687023 | 0.91 | SMN1; SMN2 (0.41) | PTGER3CNR2NPSR1 | |
| SCHEMBL687744 | 0.89 | PTGER3 (0.43) | PTGER3CNR2FFAR1SLC16A3SLC16A1 | |
| SCHEMBL687881 | 0.88 | PTGER3 (0.40) | PTGER3CNR2FFAR1SLC16A3SLC16A1 | |
| SCHEMBL687778 | 0.86 | CNR2 (0.43) | PTGER3CNR2NPSR1CTSA | |
| SCHEMBL687801 | 0.86 | FFAR1 (0.35) | FFAR1FFAR2 | |
| SCHEMBL687654 | 0.84 | PTGER3 (0.43) | PTGER3CYP1A2 | |
| SCHEMBL27762466 | 0.84 | SMN1; SMN2 (0.35) | PTGER3FFAR1CTSA | |
| SCHEMBL687640 | 0.84 | PTGER3 (0.40) | PTGER3CNR2SLC16A3SLC16A1CYP1A2 | |
| SCHEMBL688409 | 0.81 | PPARG (0.42) | PTGER3FFAR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL688317 | 0.81 | CNR2 (0.43) | PTGER3CNR2FFAR1SLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |