Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877908 | 1.00 | EPHX2 (0.48) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6875728 | 0.92 | EPHX1 (0.54) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6875734 | 0.92 | EPHX1 (0.54) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6874126 | 0.91 | MCHR1 (0.48) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6874120 | 0.91 | MCHR1 (0.48) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6465036 | 0.90 | MCHR1 (0.51) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6465026 | 0.90 | MCHR1 (0.51) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6873277 | 0.89 | EPHX2 (0.56) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6873271 | 0.89 | EPHX2 (0.56) | EPHX2ADRA2AMCHR1 | |
| SCHEMBL6873270 | 0.89 | SMN1; SMN2 (0.53) | ADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |