Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.50 |
| ▸ | UBE2M | P61081 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873277 | 1.00 | EPHX2 (0.56) | EPHX2MCHR1ADRA2ADCUN1D1UBE2M | |
| SCHEMBL6874120 | 0.91 | MCHR1 (0.48) | EPHX2MCHR1ADRA2ADCUN1D1UBE2M | |
| SCHEMBL6874126 | 0.91 | MCHR1 (0.48) | EPHX2MCHR1ADRA2ADCUN1D1UBE2M | |
| SCHEMBL6876190 | 0.90 | LMNA (0.57) | EPHX2MCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6876195 | 0.90 | LMNA (0.57) | EPHX2MCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6877906 | 0.89 | EPHX2 (0.48) | EPHX2MCHR1ADRA2A | |
| SCHEMBL6877908 | 0.89 | EPHX2 (0.48) | EPHX2MCHR1ADRA2A | |
| SCHEMBL6868229 | 0.89 | KMT2A (0.53) | EPHX2MCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6868233 | 0.89 | KMT2A (0.53) | EPHX2MCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6873734 | 0.88 | CXCR3 (0.47) | EPHX2MCHR1ADRA2ACXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |