Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877947 | 1.00 | EPHX1 (0.46) | EPHX1EPHX2MCHR1ADRA2AHTR1A | |
| SCHEMBL6875427 | 0.97 | MCHR1 (0.45) | EPHX1EPHX2MCHR1ADRA2AHTR1A | |
| SCHEMBL6875432 | 0.97 | MCHR1 (0.45) | EPHX1EPHX2MCHR1ADRA2AHTR1A | |
| SCHEMBL6876994 | 0.87 | KDM4E (0.50) | MCHR1ADRA2A | |
| SCHEMBL6877000 | 0.87 | KDM4E (0.50) | MCHR1ADRA2A | |
| SCHEMBL6874577 | 0.83 | LMNA (0.52) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6874583 | 0.83 | LMNA (0.52) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6877613 | 0.82 | MCHR1 (0.48) | EPHX1EPHX2MCHR1ADRA2AHTR1A | |
| SCHEMBL6868157 | 0.82 | MCHR1 (0.49) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6868164 | 0.82 | MCHR1 (0.49) | EPHX1MCHR1ADRA2AHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |