Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877953 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TP53L3MBTL1CXCR5ABCB11 | |
| SCHEMBL6874502 | 0.85 | MCHR1 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6874497 | 0.85 | MCHR1 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877203 | 0.84 | USP2 (0.48) | ALDH1A1MCHR1HCRTR1HCRTR2 | |
| SCHEMBL6877198 | 0.84 | USP2 (0.48) | ALDH1A1MCHR1HCRTR1HCRTR2 | |
| SCHEMBL13793521 | 0.83 | MCHR1 (0.61) | CXCR5MCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL6877485 | 0.81 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877476 | 0.81 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877756 | 0.80 | MCHR1 (0.45) | CXCR5MCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL6877757 | 0.80 | MCHR1 (0.45) | CXCR5MCHR1ADRA2AADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |