Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878117 | 1.00 | RAB9A (0.48) | RAB9AKMT2ANPC1CHRNA7HTR3A | |
| SCHEMBL6460134 | 0.83 | MCHR1 (0.47) | RAB9AKMT2AMCHR1MEN1ADRA2A | |
| SCHEMBL6463225 | 0.83 | MCHR1 (0.47) | RAB9AKMT2AMCHR1MEN1ADRA2A | |
| SCHEMBL6879782 | 0.82 | RAB9A (0.51) | RAB9AKMT2ANPC1MCHR1MEN1 | |
| SCHEMBL6879777 | 0.82 | RAB9A (0.51) | RAB9AKMT2ANPC1MCHR1MEN1 | |
| SCHEMBL6878847 | 0.81 | MCHR1 (0.58) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6878850 | 0.81 | MCHR1 (0.58) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6874497 | 0.81 | MCHR1 (0.48) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6877882 | 0.81 | MCHR1 (0.59) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6874502 | 0.81 | MCHR1 (0.48) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |