Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.83 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.83 |
| ▸ | MCHR1 | Q99705 | 18/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.77 |
| ▸ | HRH1 | P35367 | 6/20 | 0.77 |
| ▸ | HTR2B | P41595 | 5/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458796 | 0.91 | CNR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6458806 | 0.91 | CNR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6463657 | 0.89 | MCHR1 (0.84) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6463650 | 0.89 | MCHR1 (0.84) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6465507 | 0.89 | MCHR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6875387 | 0.89 | MCHR1 (0.75) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6465510 | 0.89 | MCHR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6875396 | 0.89 | MCHR1 (0.75) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6868500 | 0.88 | MCHR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL6868504 | 0.88 | MCHR1 (1.00) | CNR1KCNH2AURKBMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |