SCHEMBL6878690

SCHEMBL6878690

CC(C)(CCCCBr)OC1CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887481 0.98 MEN1 (0.34) MEN1KMT2A
SCHEMBL9169426 0.95 MEN1 (0.30) MEN1KMT2A
SCHEMBL9174749 0.88
SCHEMBL19687861 0.85 ALDH1A1 (0.35) MEN1KMT2A
SCHEMBL21025725 0.83 CYP1A2 (0.34) MEN1KMT2A
SCHEMBL12092690 0.80 ACACB (0.35) MEN1KMT2A
SCHEMBL3283774 0.80 MEN1 (0.35) MEN1KMT2A
SCHEMBL187033 0.78 MEN1 (0.36) MEN1KMT2A
SCHEMBL9170155 0.78
SCHEMBL16314438 0.78 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1282636-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-11-01 CN disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN disclosed
EP-0675878-B1 NOVEL VITAMIN D ANALOGUES LEO PHARM PROD LTD (DK) 1997-01-29 EP disclosed
US-5554599-A ANTIINFLAMMATORY AND IMMUNOMODULATING AGENTS; PSORIASIS, OSTEOPOROSIS, OSTEOGENESIS LEO PHARMACEUTICAL PRODUCTS LTD. (DK) 1996-09-10 US disclosed
EP-0675878-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1995-10-11 EP disclosed
US-5401732-A Autoimmune diseases LEO PHARMACEUTICAL PRODUCTS LTD. A/S KEMISKE FABRIK PRODUKIONSAKTIESE SKAB (DK) 1995-03-28 US disclosed
US-5378695-A Autoimmune diseases; antidiabetic, antiinflammatory, antiarthritic, antiasthmatic and hypotensive agents LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1995-01-03 US disclosed
WO-1994014766-A1 NOVEL VITAMIN D ANALOGUES Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1994-07-07 WO disclosed
EP-0460032-B1 NOVEL VITAMIN D ANALOGUES LEO PHARM PROD LTD (DK) 1994-04-27 EP disclosed
EP-0460034-B1 NOVEL VITAMIN D ANALOGUES LEO PHARM PROD LTD (DK) 1994-04-27 EP disclosed
EP-0460034-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1991-12-11 EP disclosed
EP-0460032-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1991-12-11 EP disclosed
WO-1990009992-A1 NOVEL VITAMIN D ANALOGUES Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1990-09-07 WO disclosed
WO-1990009991-A1 NOVEL VITAMIN D ANALOGUES Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1990-09-07 WO disclosed