Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 16/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878907 | 1.00 | MCHR1 (0.61) | MCHR1ADRA2ANPY5REPHX2ACP1 | |
| Hydrochloric Acid SCHEMBL6456269 | 0.99 | MCHR1 (0.60) | MCHR1ADRA2ANPY5REPHX2ACP1 | |
| SCHEMBL6463026 | 0.91 | MCHR1 (0.75) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL6456014 | 0.90 | MCHR1 (0.74) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6876013 | 0.89 | MCHR1 (0.52) | MCHR1ADRA2ANPY5REPHX2ACP1 | |
| SCHEMBL6876020 | 0.89 | MCHR1 (0.52) | MCHR1ADRA2ANPY5REPHX2ACP1 | |
| SCHEMBL6875075 | 0.89 | MCHR1 (0.50) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6880013 | 0.88 | MCHR1 (0.49) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6456819 | 0.88 | MCHR1 (0.49) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL6462112 | 0.86 | ADRA2A (0.55) | MCHR1ADRA2ANPY5REPHX2ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |