Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 4/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879043 | 1.00 | MCHR1 (0.46) | MCHR1ADRA2ACCNKCDK12CCNA2 | |
| SCHEMBL6874877 | 0.87 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RGPR6LMNA | |
| SCHEMBL6874880 | 0.87 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RGPR6LMNA | |
| SCHEMBL6875830 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RLMNAKDM4E | |
| SCHEMBL6876564 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RLMNAKDM4E | |
| SCHEMBL6875826 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RLMNAKDM4E | |
| SCHEMBL6876570 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RLMNAKDM4E | |
| SCHEMBL13793567 | 0.84 | MCHR1 (0.65) | MCHR1ADRA2ANPY5RLMNAMEN1 | |
| SCHEMBL6880806 | 0.84 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RLMNAKDM4E | |
| SCHEMBL6880801 | 0.84 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |