Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885567 | 0.90 | ADORA2A (0.52) | ADORA2AALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL6876856 | 0.86 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6883010 | 0.84 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6883012 | 0.81 | ADORA2A (0.44) | ADORA2ANPC1 | |
| SCHEMBL6883434 | 0.81 | ADORA2A (0.46) | ADORA2AALDH1A1HPGDKDM4E | |
| SCHEMBL6884874 | 0.80 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6884609 | 0.80 | ADORA2A (0.79) | ADORA2AALDH1A1 | |
| SCHEMBL6879136 | 0.78 | ADORA2A (0.70) | ADORA2AALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL18269280 | 0.77 | ADORA2A (0.58) | ADORA2AALDH1A1HPGDLMNA | |
| SCHEMBL6884088 | 0.77 | ADORA2A (0.70) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889082-B2 | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-13 | — | — | US | disclosed |
| US-9889082-B2 | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-13 | — | — | US | disclosed |
| US-6689790-B2 | 8-AMINO-6-AMIDO-SUBSTITUTED-(1,2,4)TRIAZOLO(1,5-A)PYRIDINES; ADENOSINE RECEPTOR MODULATERS | HOFFMANN-LA ROCHE INC. | 2004-02-10 | — | — | US | disclosed |