Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868631 | 0.88 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6868624 | 0.88 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6463357 | 0.88 | SMYD3 (0.55) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6463349 | 0.88 | SMYD3 (0.55) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6877119 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6877116 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| Hydrochloric Acid SCHEMBL6463508 | 0.87 | SMYD3 (0.54) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| Hydrochloric Acid SCHEMBL6463513 | 0.87 | SMYD3 (0.54) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6876170 | 0.84 | MCHR1 (0.59) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6873114 | 0.83 | MCHR1 (0.74) | MCHR1ADRA2AADRA1AHTR2BHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |