Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879276 | 1.00 | MCHR1 (0.58) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6877400 | 0.86 | MCHR1 (0.58) | MCHR1ADRA2ARAB9A | |
| SCHEMBL6877394 | 0.86 | MCHR1 (0.58) | MCHR1ADRA2ARAB9A | |
| Hydrochloric Acid SCHEMBL6455956 | 0.83 | MCHR1 (0.52) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6461509 | 0.83 | MCHR1 (0.66) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6461515 | 0.83 | MCHR1 (0.66) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL6455962 | 0.83 | MCHR1 (0.52) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL6457539 | 0.82 | MCHR1 (0.65) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL6457534 | 0.82 | MCHR1 (0.65) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| Trifluoroacetic Acid SCHEMBL6467012 | 0.81 | ADRA2A (0.48) | MCHR1ADRA2AADRA1AHRH1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |