Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827280 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL3163754 | 0.82 | HPGD (0.38) | ALDH1A1CYP2B6SMN1; SMN2CHRM3HPGD | |
| Hydrochloric Acid SCHEMBL28286231 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL3661207 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL472332 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL10277739 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL4637127 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL1954054 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP2B6TSHRCYP2C19CYP2D6 | |
| SCHEMBL11546415 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRHIF1ASMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL7359984 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CYP2B6CYP2C19HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042372-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2004-07-14 | — | — | EP | claimed |
| EP-0042622-B1 | Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-08-19 | — | — | EP | claimed |
| EP-0027620-B1 | 2,2,6,6-TETRAALKYL-4-PIPERIDYL-BIS-SPIRO-ETHERS AND SYNTHETIC POLYMERS STABILISED THEREWITH | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1985-07-24 | — | — | EP | claimed |
| US-4405736-A | 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | claimed |
| EP-0042622-B1 | Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-08-19 | — | — | EP | disclosed |
| EP-0045358-B1 | 2,2,6,6-TETRAMETHYL-4-PIPERIDYL SPIRO ALIPHATIC ETHERS AS STABILIZERS FOR SYNTHETIC POLYMERS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1985-08-14 | — | — | EP | disclosed |
| EP-0027620-B1 | 2,2,6,6-TETRAALKYL-4-PIPERIDYL-BIS-SPIRO-ETHERS AND SYNTHETIC POLYMERS STABILISED THEREWITH | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |
| US-4405736-A | 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4378443-A | 2,2,6,6-Tetraalkyl-4-piperidyl-bix-spiro-ethers as light stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-03-29 | — | — | US | disclosed |
| US-4351915-A | OXIDATION AND HEAT RESISTANCE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-09-28 | — | — | US | disclosed |
| EP-0045358-A2 | 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers as stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1982-02-10 | — | — | EP | disclosed |
| EP-0042622-A1 | Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |
| EP-0027620-A1 | 2,2,6,6-Tetraalkyl-4-piperidyl-bis-spiro-ethers and synthetic polymers stabilised therewith | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-04-29 | — | — | EP | disclosed |
| EP-0022997-A1 | 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines and synthetic polymer compositions stabilized thereby | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-01-28 | — | — | EP | disclosed |
| US-4232152-A | POLYURETHANE CATALYSTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4223139-A | CATALYSTS FOR POLYURETHANE SYNTHESIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1980-09-16 | — | — | US | disclosed |
| US-4204062-A | CATALYSTS FOR POLYURETHANE SYNTHESIS | AIR PRODUCTS & CHEMICALS, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4134994-A | CATALYSTS FOR POLYURETHANE SYNTHESIS, EXHIBIT DELAYED ACTION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4086213-A | FOR POLYURETHANE SYNTHESIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1978-04-25 | — | — | US | disclosed |