Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879421 | 1.00 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL6573236 | 0.87 | ADORA3 (0.61) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL6573247 | 0.87 | ADORA3 (0.61) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL6576712 | 0.87 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6572907 | 0.86 | ADORA3 (0.65) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL6572865 | 0.86 | ADORA3 (0.56) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6878740 | 0.86 | ADORA3 (0.56) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6573828 | 0.85 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6573833 | 0.85 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6573906 | 0.85 | ADORA1 (0.56) | ADORA1ADORA3ADORA2AADORA2BPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |