Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879485 | 1.00 | FDPS (0.63) | FDPSACHEBCHEAPPALDH1A1 | |
| SCHEMBL6882597 | 0.96 | FDPS (0.58) | FDPSACHEBCHEAPPALDH1A1 | |
| SCHEMBL6882602 | 0.96 | FDPS (0.58) | FDPSACHEBCHEAPPALDH1A1 | |
| SCHEMBL6875479 | 0.89 | FDPS (0.50) | FDPSALDH1A1HPGDHTTKDM4E | |
| SCHEMBL6875471 | 0.89 | FDPS (0.50) | FDPSALDH1A1HPGDHTTKDM4E | |
| SCHEMBL4421209 | 0.88 | FDPS (0.81) | FDPSACHEBCHEAPPKDM4E | |
| SCHEMBL6882991 | 0.87 | FDPS (0.56) | FDPSACHEBCHEAPPALDH1A1 | |
| SCHEMBL6882986 | 0.87 | FDPS (0.56) | FDPSACHEBCHEAPPALDH1A1 | |
| SCHEMBL13934765 | 0.85 | FDPS (0.62) | FDPSACHEBCHEAPPKDM4E | |
| SCHEMBL4419931 | 0.84 | FDPS (0.70) | FDPSACHEBCHEAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833421-B1 | Compound | ROLIC AG (CH) | 2004-12-21 | — | — | US | disclosed |
| EP-1200494-B1 | COMPOUND | ROLIC AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| EP-1200494-A1 | COMPOUND | Rolic AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001007495-A1 | COMPOUND | ROLIC AG (CH) | 2001-02-01 | — | — | WO | disclosed |