Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 11/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688379 | 0.96 | PTGER3 (0.42) | PTGER3CNR2CTSASLC22A12CYP26A1 | |
| SCHEMBL688878 | 0.94 | PTGER3 (0.41) | PTGER3CNR2CTSASLC22A12CYP26A1 | |
| SCHEMBL688474 | 0.91 | PTGER3 (0.39) | PTGER3CNR2CTSASLC22A12PYGL | |
| SCHEMBL688442 | 0.90 | PTGER3 (0.42) | PTGER3CNR2CTSASLC22A12CYP26A1 | |
| SCHEMBL688053 | 0.90 | PTGER3 (0.43) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL687228 | 0.89 | GNRHR (0.39) | PTGER3CTSAITGB1ITGA4 | |
| SCHEMBL687045 | 0.88 | PTGER3 (0.42) | PTGER3CNR2CTSASLC22A12CYP26A1 | |
| SCHEMBL687923 | 0.88 | PTGER3 (0.41) | PTGER3CNR2CTSASLC22A12ITGB1 | |
| SCHEMBL686799 | 0.88 | PTGER3 (0.51) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL688215 | 0.88 | PTGER3 (0.43) | PTGER3CTSAITGB1ITGA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |