Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011450 | 1.00 | GAA (0.52) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL9217074 | 0.91 | GAA (0.54) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL10037152 | 0.88 | GAA (0.51) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL10037208 | 0.85 | GAA (0.49) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL10037207 | 0.85 | GAA (0.49) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL5885882 | 0.82 | GAA (0.46) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL19989287 | 0.82 | ALDH1A1 (0.46) | HPGDL3MBTL1ALDH1A1PKM | |
| SCHEMBL19989286 | 0.82 | ALDH1A1 (0.46) | HPGDL3MBTL1ALDH1A1PKM | |
| SCHEMBL29859198 | 0.82 | ALDH1A1 (0.46) | HPGDL3MBTL1ALDH1A1PKM | |
| SCHEMBL29110399 | 0.79 | NPSR1 (0.51) | GAAHPGDL3MBTL1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091407-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLP (US) | 2011-07-28 | — | — | WO | disclosed |