⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327529 | 1.00 | — | — | |
| SCHEMBL23371688 | 1.00 | — | — | |
| SCHEMBL25594422 | 0.91 | PNMT (0.35) | — | |
| Tert-Butyl Formate SCHEMBL27992301 | 0.79 | TDP1 (0.45) | — | |
| SCHEMBL10261526 | 0.76 | — | — | |
| SCHEMBL10261945 | 0.76 | — | — | |
| SCHEMBL1360201 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL22999867 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4510205 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9951227 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012092168-A1 | FUSED 6,5 BICYCLIC RING SYSTEM P2 LIGANDS, AND METHODS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION (US) | 2012-07-05 | — | — | WO | claimed |
| WO-2012092188-A1 | HYDROGEN BOND FORMING P1 LIGANDS AND METHODS FOR TREATING HIV | GHOSH ARUN K (US) | 2012-07-05 | — | — | WO | claimed |
| CN-109073940-B | Liquid crystal dimming member, light-transmitting conductive film, and liquid crystal dimming element | 日东电工株式会社 | 2022-03-08 | — | — | CN | disclosed |
| CN-106716182-B | Polymerizable polysiloxane with hydrophilic substituent | 爱尔康公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-108289893-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107531691-A | Treat the derivative and method of hepatitis B infection | 诺维拉治疗公司 | 2018-01-02 | — | — | CN | disclosed |
| US-20170137405-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. | 2017-05-18 | — | — | US | disclosed |
| US-9540343-B2 | Compounds for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9499558-B2 | Compounds and methods for treating HIV | PURDUE RESEARCH FOUNDATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150225414-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-08-13 | — | — | US | disclosed |
| US-9024038-B2 | Compunds and methods for treating HIV | PURDUE RESEARCH FOUNDATION (US) | 2015-05-05 | — | — | US | disclosed |
| US-8546442-B2 | Pyrazolopiperidine compounds as CCR1 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| US-20120322790-A1 | Pyrazolopiperidine Compounds As CCR1 Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2012092168-A1 | FUSED 6,5 BICYCLIC RING SYSTEM P2 LIGANDS, AND METHODS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION (US) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012092188-A1 | HYDROGEN BOND FORMING P1 LIGANDS AND METHODS FOR TREATING HIV | GHOSH ARUN K (US) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012087782-A1 | PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | IRM, LLC | 2004-12-02 | — | — | US | disclosed |
| EP-0567015-B1 | Method of and apparatus for cleaning oil-deposited material | MITSUBISHI CHEM CORP (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5399203-A | Cleaning agent for floating and separation of oil, washing with water and steam | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0567015-A1 | Method of and apparatus for cleaning oil-deposited material and a cleaning agent used therefor | Mitsubishi Chemical Corporation (JP) | 1993-10-27 | — | — | EP | disclosed |